HLSG600 Wet Granulation Machine
HLSG600 Wet Granulation Machine
HLSG high efficiency mixing granulator for dry mixing and wet granulation.
The mixing and granulation of the powder is accomplished by a combination of a stirring paddle, a cutter, and a spray system.
The auxiliary machine is placed in the technical area, and the layout is optimized according to GMP requirements and safety regulations. It can be integrated with the whole granulation machine, wet granulation and drying in a fluidized bed in a closed system.
With the increasing demand for OEB3-5 powder treatment, granulation, tablet pressing, capsule filling and coating production and R&D equipment. SMA timely launch all kinds of high sealed solid preparation line, to meet the market needs.
The design of enclosed equipment must be a risk-based solution. Conduct a preliminary analysis of key and potential risks to the process and plant conditions in which the drug will be used, such as regulations, layout, and industrial objectives.
The αβ valve is fed with high-activity powder, and the closed chamber adopts pneumatic sealing ring, which will not be deflated after power failure to ensure complete sealing and isolation of the production area.
The closed chamber is made of stainless steel AISI304, which maintains a slight negative pressure during production.
The side door has the function of automatic locking and detection when the machine is turned on, so as to prevent operators from misoperation and causing injuries to personnel. Inflatable sealing ring is adopted.
The purified air passed through the junior high HEPA filter is sent to the main engine by the blower, and the exhaust air is filtered by the dust collector and the bag in bag out HEPA filter, and then discharged to the outdoor by the exhaust fan. During the whole production process, the micro-negative pressure of -50Pa is maintained in the host cavity.
All parts that come into contact with the product will be wetted or subjected to a more rigorous and sophisticated online cleaning process based on an operational risk control analysis prior to removal.
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TECHNICAL PARAMETER |
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Capacity(liters) |
Working Capacity(liters) |
Motor Power(kw) |
Impeller Speed(RPM) |
Chopper Speed(RPM) |
Weight(kg) |
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600 |
Minimum20% Maximum70% |
30 |
10-130 |
Inverter control maximum up to 2000 |
2800 |
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